The Rise of the Machines: Why the future lies with less injurious adaptive ventilation strategies

It has been 60 years since Bendixen, Hedley-White, and Laver described the progressive atelectasis resultant hypoxemia that resulted from prolonged mechanical ventilation. A proposed solution was to raise tidal volume (VT) those recommended by Radford’s nomogram for “proper ventilation” 10 -15 ml/ kg. less than four later Acute Respiratory Distress Syndrome (ARDS) first reported. Since then, clinicians researchers have searching ideal ventilation strategy minimise harm optimise outcomes ventilatory support in critically ill.